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The generally accepted definition of health is "a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity"

Saturday, March 28, 2009

Dietary mineral

Dietary minerals are the chemical elements required by living organisms, other than the four elements carbon, hydrogen, nitrogen, and oxygen present in common organic molecules. The term "mineral" is archaic, since the intent of the definition is to describe ions, not chemical compounds or actual minerals.

Dietitians may recommend that minerals are best supplied by ingesting specific foods rich with the element(s) of interest. Sometimes minerals are ingested as mineral dietary supplements, the most common being iodine in iodized salt.

The dietary focus on minerals derives from an interest in supporting biochemical reactions with the required elemental components. Appropriate intake levels of certain chemical elements are thus required to maintain optimal health. According to nutritional experts, the requirements are met simply with a conventional balanced diet.

Essential minerals

Some sources state that sixteen minerals are required to support human biochemical processes by serving structural and functional roles as well as electrolytes: The term "dietary minerals" does not include the fundamental elements of organic chemistry: hydrogen, carbon, nitrogen, and oxygen. Also, sometimes a distinction is drawn between this category and micronutrients. Most of the essential minerals of relatively low atomic weight:

H He
Li Be B C N O F Ne
Na Mg Al Si P S Cl Ar
K Ca Sc Ti V Cr Mn Fe Co Ni Cu Zn Ga Ge As Se Br Kr
Rb Sr Y Zr Nb Mo Tc Ru Rh Pd Ag Cd In Sn Sb Te I Xe
Cs Ba La * Hf Ta W Re Os Ir Pt Au Hg Tl Pb Bi Po At Rn
Fr Ra Ac ** Rf Db Sg Bh Hs Mt Ds Rg
* Ce Pr Nd Pm Sm Eu Gd Tb Dy Ho Er Tm Yb Lu
** Th Pa U Np Pu Am Cm Bk Cf Es Fm Md No Lr
The four organic basic elements Quantity elements Essential trace elements Pervasive but no identified biological function in humans

The following play important roles in biological processes:

zinc toxicity
Mineral RDA/AI Description Category Insufficiency Excess
Potassium
4700 mg Quantity is a systemic electrolyte and is essential in coregulating ATP with sodium. Dietary sources include legumes, potato skin, tomatoes, and bananas. hypokalemia
hyperkalemia
Chloride
2300 mg Quantity is needed for production of hydrochloric acid in the stomach and in cellular pump functions. Table salt is the main dietary source of chloride. hypochloremia
hyperchloremia
Sodium
1500 mg Quantity is a systemic electrolyte and is essential in coregulating ATP with potassium. Dietary sources include table salt (sodium chloride, the main source), sea vegetables, milk, and spinach. hyponatremia
hypernatremia
Calcium
1000 mg Quantity is needed for muscle, heart and digestive system health, builds bone, supports synthesis and function of blood cells. Dietary sources of calcium include dairy products, canned fish with bones (salmon, sardines), green leafy vegetables, nuts and seeds. hypocalcaemia
hypercalcaemia
Phosphorus
700 mg Quantity is a component of bones (see apatite) and energy processing and many other functions. In biological contexts, usually seen as phosphate. hypophosphatemia
hyperphosphatemia
Magnesium
420 mg Quantity is required for processing ATP and for bones. Dietary sources include nuts, soy beans, and cocoa. hypomagnesemia,
magnesium deficiency
hypermagnesemia
Zinc
11 mg Trace is pervasive and required for several enzymes such as carboxypeptidase, liver alcohol dehydrogenase, and carbonic anhydrase.
Iron
8 mg Trace is required for many proteins and enzymes, notably hemoglobin. Dietary sources include red meat, leafy green vegetables, fish (tuna, salmon), eggs, dried fruits, beans, whole grains, and enriched grains. iron deficiency
iron overload disorder
Manganese
2.3 mg Trace is a cofactor in enzyme functions. manganese deficiency
manganism
Copper
900 µg Trace is required component of many redox enzymes, including cytochrome c oxidase. copper deficiency
copper toxicity
Iodine
150 µg Trace is required for the biosynthesis of thyroxine. iodine deficiency

Selenium
55 µg Trace a cofactor essential to activity of antioxidant enzymes like glutathione peroxidase. selenium deficiency
selenosis

Molybdenum
45 µg Trace the oxidases xanthine oxidase, aldehyde oxidase, and sulfite oxidase molybdenum deficiency


Other elements

Many elements have been suggested as essential, but such claims have usually not been confirmed. Definitive evidence for efficacy comes from the characterization of a biomolecule containing the element with an identifiable and testable function. One problem with identifying efficacy is that some elements are innocuous at low concentrations and are pervasive, so proof of efficacy is lacking because deficiencies are difficult to reproduce.

  • Relatively large quantities of sulfur are required, but there is no RDA, as the sulfur is obtained from and used for amino acids, and therefore should be adequate in any diet containing enough protein.
  • Cobalt is required in the synthesis of vitamin B12, but because bacteria are required to synthesize the vitamin, it is usually considered part of vitamin B12 deficiency rather than its own mineral deficiency.
  • There have been occasional studies asserting the essentiality of nickel, but it currently has no known RDA.
  • Chromium is sometimes described as essential. It is implicated in sugar metabolism in humans, leading to a market for the supplement, chromium picolinate, but definitive biochemical evidence for a physiological function is lacking.
  • Fluoride has been described as conditionally essential, depending upon the importance placed upon the prevention of chronic disease.
Arsenic, boron, bromine, cadmium, silicon, tungsten, and vanadium have established, albeit specialized, biochemical roles as structural or functional cofactors in other organisms. These elements appear not to be utilized by humans.

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